On June 28, 2016
Albumin coated bone allograft is a new bone replacement material, with a minimal manufacturing modification of the human bone graft, which is well-known and widely used for decades. Originally the graft is processed with Urist’s method, partially decalcified, sterilized and lyophilized. It has been successfully used in Hungary for two decades. In orthopedy, traumatology, neurosurgery, maxillofacial and dento-alveolar surgery neither „serious adverse event” nor „serious complications” has occurred in the last 20 years. At the end of the original bone graft manufacturing process, the graft surface is submerged into a 10% serum albumin solution, which is manufactured in Gödöllő, Hungary, and then the graft is lyophilized again in aseptic conditions. The whole surface, including the inner pores, is covered with a uniform layer of albumin, which does not cause difference in the clinical use of the graft. Albumin infusion is typically used for healing seriously ill person, like burnt or polytraumatized patients, in order to facilitate the regeneration. The same effect is used for accelerating the integration of the bone graft.